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. Author manuscript; available in PMC: 2007 Oct 1.
Published in final edited form as: Virology. 2007 Jan 26;362(1):109–119. doi: 10.1016/j.virol.2006.12.026

Figure 5. Geldanamycin destabilization of VSV L protein requires proteosome function.

Figure 5

A) BHK cells were infected with VSV, and 5hpi left untreated, treated with geldanamycin, or treated with both geldanamycin and proteosome inhibitor. Pulse-chase results for 10 minute and 30 minute chases are shown. B) Stability of L protein in the proteins presence (△) or absence (■) of 5μM geldanamycin and in the presence of geldanamycin and a proteosome inhibitor (◆, dotted line). Levels are expressed as a percentage of the signal that was present at the 10 minute chase. Values are the average of three separate experiments +/- standard deviation.