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Relative prepro-TRH expression as assessed by laser densitometry in the rostral and caudal PVN of WT (open circles) and TR-β2–null (KO; filled circles) mice. Data shown are mean ± SEM. Each point represents analysis of anatomically identical sections from three separate animals. AP < 0.05 versus hypo and hyper WT, respectively, by ANOVA. BP < 0.05 versus WT in the same treatment group. Hypo, PTU–treated mice; Euth, untreated mice (basal conditions); Hyper, T3-treated mice.
