Table 1. SAPK/JNK Substrates.
Table 1 represents a list of known JNK substrates. The list is not comprehensive but representative.
Transcription |
c-Jun |
JunD |
ATF2 |
ATF3 |
Elk 1 |
Elk-3 |
.p53 |
RXRα |
RARα |
Androgen receptor |
NFAT4 |
HSF-1 |
c-Myc |
Nuclear Pore Complex |
Nup214 |
Apoptosis |
Smac |
Bim |
Bmf |
Bcl-2 |
Bcl-XL |
Mcl-1 |
Microtubules |
Tau |
MAP1 |
MAP2A |
DCX (doublecortin) |
Amyloid β Precursor Protein |
Signaling |
IRS-1 |
Paxillin |
14-3-3 |