Table 2.
Logistic regression model for morphine dose
| Parameter | p-value | Odds Ratio | 95% Lower Bound | 95% Upper Bound |
|---|---|---|---|---|
| Joint genotype groups | 0.05 | |||
| a. Met/Met & AA | 0.012 | 0.278 | 0.102 | 0.756 |
| b. AA but not Met/Met | 0.280 | 0.625 | 0.266 | 1.467 |
| c. Met/Met but not AA | 0.191 | 0.240 | 0.028 | 2.039 |
| Months using morphine | 0.005 | 1.106 | 1.031 | 1.186 |
| Time since cancer diagnosis (in months) | 0.006 | 0.988 | 0.980 | 0.987 |
Morphine dose (low=≤ 117mg/24H; high>117mg/24h)
Reference variable is Neither Met/Met nor AA
Candidate variables included months using morphine, time since cancer diagnosis, age, sex, Karnofsky performance status, serum albumin, serum creatinine