Table 2.
Additive Genetic Model – ordered by GEE (2a) and FBAT (2b) p-value Results
| Phenotype | SNP | Chromosome | Position | GEE P value | FBAT P value | Gene |
|---|---|---|---|---|---|---|
| 2a. Results ordered by GEE p-value results | ||||||
| AF | rs958546 | 13 | 45,731,718 | 4.78E-06 | 0.104 | |
| Major CVD | rs499818 | 6 | 13,440,446 | 6.64E-06 | 0.17 | |
| AF | rs4776472 | 15 | 67,793,927 | 7.87E-06 | 0.042 | |
| HF | rs740363 | 10 | 118,565,596 | 8.82E-06 | 0.065 | KIAA1598 |
| AF | rs10501920 | 11 | 98,998,383 | 9.40E-06 | 0.448 | CNTN5 |
| Major CHD | rs2549513 | 16 | 78,108,228 | 9.65E-06 | 0.106 | |
| AF | rs10507539 | 13 | 45,732,707 | 1.05E-05 | 0.02 | |
| Major CVD | rs1512411 | 6 | 13,439,076 | 1.55E-05 | 0.366 | PHACTR1, TBC1D7 |
| Major CVD | rs10511701 | 9 | 22,102,599 | 1.67E-05 | 0.132 | |
| Major CVD | rs1556516 | 9 | 22,090,176 | 1.86E-05 | 0.071 | |
| Major CVD | rs1537371 | 9 | 22,089,568 | 1.87E-05 | 0.068 | |
| Major CHD | rs10497726 | 2 | 192,876,826 | 1.98E-05 | 0.046 | TMEFF2 |
| Major CHD | rs2962994 | 15 | 55,129,991 | 1.98E-05 | 0.279 | TCF12 |
| Major CHD | rs997651 | 17 | 61,344,845 | 2.28E-05 | 0.547 | MGC33887 |
| Major CVD | rs2148079 | 13 | 109,989,414 | 2.33E-05 | 0.026 | RAB20 |
| AF | rs10501918 | 11 | 98,971,412 | 2.40E-05 | 0.093 | CNTN5 |
| HF | rs10511633 | 9 | 17,151,527 | 2.59E-05 | 0.044 | C9orf39 |
| Major CHD | rs7836535 | 8 | 96,774,748 | 2.63E-05 | 0.003 | |
| Major CHD | rs1820996 | 15 | 55,120,501 | 2.83E-05 | 0.218 | TCF12 |
| Major CHD | rs213168 | 15 | 55,028,949 | 3.09E-05 | 0.278 | TCF12 |
| Major CHD | rs997652 | 17 | 61,344,827 | 3.22E-05 | 0.613 | MGC33887 |
| AF | rs4590838 | 11 | 97,372,875 | 4.03E-05 | 0.248 | |
| Major CHD | rs10516882 | 4 | 92,265,754 | 4.33E-05 | 0.858 | |
| Major CVD | rs1742083 | 14 | 90,256,423 | 5.23E-05 | 0.138 | TTC7B |
| Major CVD | rs507369 | 6 | 13,440,039 | 6.23E-05 | 0.137 | PHACTR1, TBC1D7 |
| 2b. Results Ordered by FBAT | ||||||
| Major CHD | rs10505879 | 12 | 22,539,123 | 0.058 | 3.06E-05 | KIAA0528 |
| Major CVD | rs39312 | 7 | 116,548,736 | 0.138 | 4.37E-05 | WNT2 |
| AF | rs10511311 | 3 | 113,538,529 | 0.003 | 4.45E-05 | CD200 |
| AF | rs1427828 | 12 | 88,264,967 | 0.018 | 4.58E-05 | DUSP6 |
| HF | rs10515869 | 5 | 163,444,804 | 0.029 | 4.72E-05 | |
| AF | rs1751382 | 14 | 67,762,403 | 0.138 | 5.14E-05 | RAD51L1 |
| AF | rs1314913 | 14 | 67,769,347 | 0.126 | 5.53E-05 | RAD51L1 |
| AF | rs262467 | 6 | 120,497,469 | 0.117 | 6.39E-05 | |
| AF | rs412253 | 4 | 31,119,019 | 0.086 | 6.55E-05 | |
| Major CVD | rs39317 | 7 | 116,560,255 | 0.219 | 6.72E-05 | WNT2, ASZ1 |
| Major CVD | rs9886209 | 7 | 116,599,175 | 0.594 | 6.95E-05 | ASZ1 |
| Major CVD | rs10493900 | 1 | 98,357,234 | 0.801 | 7.10E-05 | |
| AF | rs1298340 | 14 | 67,747,245 | 0.275 | 7.40E-05 | RAD51L1 |
| Major CVD | rs2452503 | 10 | 60,686,639 | 0.384 | 9.94E-05 | FAM13C1 |
| AF | rs324735 | 4 | 77,062,193 | 0.018 | 9.98E-05 | |
| Major CHD | rs580069 | 11 | 121,794,555 | 0.074 | 1.24E-04 | |
| AF | rs1604355 | 1 | 187,190,664 | 0.294 | 1.29E-04 | FAM5C |
| Major CHD | rs559453 | 11 | 121,794,482 | 0.073 | 1.32E-04 | |
| Major CHD | rs951442 | 15 | 31,705,234 | 0.003 | 1.35E-04 | RYR3 |
| HF | rs1176486 | 10 | 132,315,529 | 0.165 | 1.49E-04 | |
| AF | rs2421954 | 2 | 63,665,926 | 0.003 | 1.51E-04 | LOC51057 |
| HF | rs9313999 | 5 | 163,444,569 | 0.015 | 1.55E-04 | |
| AF | rs7676376 | 4 | 158,199,764 | 0.282 | 1.72E-04 | PDGFC |
| Major CHD | rs10501127 | 11 | 33,698,233 | 0.251 | 1.78E-04 | CD59 |
| AF | rs1163397 | 3 | 110,400,929 | 0.002 | 1.78E-04 | |