Table 4.
Top Results for Geometric Means of SBP and DBP Considered Jointly (at examinations 1, 7 and in the long term), and arterial stiffness phenotypes considered jointly.
| SNP | Exam | Chr. | Position | P value | Gene |
|---|---|---|---|---|---|
| DBP and SBP | |||||
| rs10493340 | 1 | 1 | 63,303,150 | 1.49 × 10-5 | |
| rs9321764 | 7 | 6 | 140,532,157 | 2.89 × 10-5 | |
| rs10491334 | 7 | 5 | 110,800,303 | 3.74 × 10-5 | CAMK4 |
| rs2121070 | 1 | 14 | 75,720,517 | 3.96 × 10-5 | C14orf118 |
| rs1328925 | 1 | 4 | 159,547,895 | 4.22 × 10-5 | TMEM144 |
| rs10510079 | 1 | 10 | 122,473,101 | 7.27 × 10-5 | |
| rs7562854 | 7 | 2 | 12,149,816 | 7.52 × 10-5 | |
| rs1841055 | 7 | 4 | 70,039,785 | 7.63 × 10-5 | UGT2A3 |
| rs10485320 | 7 | 6 | 47,884,860 | 7.75 × 10-5 | OPN5 |
| rs9298203 | 7 | 8 | 73,270,276 | 8.28 × 10-5 | |
| Arterial stiffness | |||||
| rs10518082 | 7 | 4 | 72,282,885 | 0.002 | DCK |
| rs1322512 | 7 | 6 | 153,040,067 | 0.005 | SYNE1 |
| rs10511389 | 7 | 3 | 120,557,547 | 0.007 | CDGAP |
| rs883524 | 7 | 8 | 23,250,536 | 0.008 | LOXL2 |
| rs965674 | 7 | 5 | 82,518,340 | 0.008 | XRCC4 |
| rs10502173 | 7 | 11 | 112,708,233 | 0.009 | TTC12 |
| rs1468512 | 7 | 17 | 64,731,363 | 0.010 | ABCA10 |
| rs4075701 | 7 | 2 | 116,146,020 | 0.011 | |
| rs10496604 | 7 | 2 | 123,501,987 | 0.011 | |
| rs770189 | 7 | 5 | 88,124,195 | 0.011 | MEF2C |
Based on Additive genetic effects model using GEE and minor allele frequency of 0.1, call rate >= 0.80 and HWE p value >= 0.001