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. 2006 Jul 27;576(Pt 1):179–189. doi: 10.1113/jphysiol.2006.111278

Figure 2. The effect of nitrobenzylthioinosine (NBTI) on adenosine outflow from cardiac fibroblasts during ATP depletion.

Figure 2

The cells were cultured in Dulbecco's modified Eagle's medium (DMEM) containing 10% fetal bovine serum and 5 mm glucose and no insulin (A), or 5 mm glucose and 10 nm insulin (B), or 25 mm glucose and no insulin (C), or 25 mm glucose and 10 nm insulin (D). No insulin refers to a concentration of 10−11m. Cells were labelled with [8-14C]adenine, and deprived of ATP as described in the legend to Fig. 1, except for the presence (•) or absence (○) of 1 μm NBTI in the glucose-free DMEM. The data represent the mean ± s.d. from three independent experiments. *P < 0.05 versus no NBTI.