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. Author manuscript; available in PMC: 2008 Sep 1.
Published in final edited form as: Biochem Pharmacol. 2007 Jun 14;74(5):787–800. doi: 10.1016/j.bcp.2007.06.008

Figure 2. Time and dose dependent synthesis of PGE2 and TXB2 in A549-TPα cells upon TP agonist I-BOP stimulation.

Figure 2

Figure 2

Cells were serum-starved for 16 h and then treated with 50 nM I-BOP or vehicle (0.1% ethanol) for varying length of time as indicated or with I-BOP at different concentrations as indicated for 6 h. The TXB2 and PGE2 in the medium were quantified with ELISA as described under MATERIALS AND METHODS. Fold increase (Fold/Basal) in PGE2 and TXB2 were presented as mean ± S.D. (n=3), where the basal levels of PGE2 and TXB2 in the medium of the control cells were assigned a value of 1.0. A. Time dependent effects of I-BOP (50 nM, 1–24 h) on PGE2 and TXB2 synthesis in A549-TPα cells. B. Dose dependent effects of I-BOP (0.1–100 nM, 24 h) on PGE2 and TXB2 synthesis in A549-TPα cells.