Table 4.
Study Group | OHTS and EGPS Control Groups | |||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|
OHTS Observation | EGPS Placebo | |||||||||||
Developed POAG | Developed POAG | Developed POAG | ||||||||||
No | Yes | No | Yes | No | Yes | |||||||
N | % | N | % | N | % | N | % | N | % | N | % | |
Race | ||||||||||||
Native American | 1 | 50.0 | 1 | 50.0 | 0 | 0 | 0 | 0 | 1 | 50.0 | 1 | 50.0 |
Asian Pacific Islander | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Black, Non Hispanic | 168 | 83.6 | 33 | 16.4 | 0 | 0 | 0 | 0 | 168 | 83.6 | 33 | 16.4 |
Hispanic | 26 | 76.5 | 8 | 23.5 | 0 | 0 | 0 | 0 | 26 | 76.5 | 8 | 23.5 |
White, Non Hispanic | 499 | 89.3 | 60 | 10.7 | 439 | 87.8 | 61 | 12.2 | 938 | 88.6 | 121 | 11.4 |
Other | 5 | 83.3 | 1 | 16.7 | 0 | 0 | 0 | 0 | 5 | 83.3 | 1 | 16.7 |
Gender | ||||||||||||
Female | 419 | 89.3 | 50 | 10.7 | 224 | 86.5 | 35 | 13.5 | 643 | 88.3 | 85 | 11.7 |
Male | 289 | 84.3 | 54 | 15.7 | 215 | 89.2 | 26 | 10.8 | 504 | 86.3 | 80 | 13.7 |
Either eye myopia worse than -1D | ||||||||||||
No | 460 | 87.3 | 67 | 12.7 | 359 | 87.8 | 50 | 12.2 | 819 | 87.5 | 117 | 12.5 |
Yes | 248 | 87.0 | 37 | 13.0 | 80 | 87.9 | 11 | 12.1 | 328 | 87.2 | 48 | 12.8 |
Self-reported medical history at baseline | ||||||||||||
Calcium channel blockers | ||||||||||||
No | 617 | 87.1 | 91 | 12.9 | 418 | 88.0 | 57 | 12.0 | 1035 | 87.5 | 148 | 12.5 |
Yes | 88 | 87.1 | 13 | 12.9 | 21 | 84.0 | 4 | 16.0 | 109 | 86.5 | 17 | 13.5 |
Beta blockers | ||||||||||||
No | 674 | 86.9 | 102 | 13.1 | 410 | 88.2 | 55 | 11.8 | 1084 | 87.3 | 157 | 12.7 |
Yes | 31 | 93.9 | 2 | 6.1 | 29 | 82.9 | 6 | 17.1 | 60 | 88.2 | 8 | 11.8 |
Diabetes | ||||||||||||
No | 613 | 86.0 | 100 | 14.0 | 414 | 87.3 | 60 | 12.7 | 1027 | 86.5 | 160 | 13.5 |
Yes | 95 | 96.0 | 4 | 4.0 | 25 | 96.2 | 1 | 3.8 | 120 | 96.0 | 5 | 4.0 |
History of heart disease | ||||||||||||
No | 665 | 87.7 | 93 | 12.3 | 392 | 88.1 | 53 | 11.9 | 1057 | 87.9 | 146 | 12.1 |
Yes | 43 | 79.6 | 11 | 20.4 | 47 | 85.5 | 8 | 14.5 | 90 | 82.6 | 19 | 17.4 |
History systemic hypertension | ||||||||||||
No | 442 | 87.7 | 62 | 12.3 | 316 | 88.5 | 41 | 11.5 | 758 | 88.0 | 103 | 12.0 |
Yes | 266 | 86.4 | 42 | 13.6 | 123 | 86.0 | 20 | 14.0 | 389 | 86.3 | 62 | 13.7 |
History of Migraine | ||||||||||||
No | 626 | 87.3 | 91 | 12.7 | 439 | 87.8 | 61 | 12.2 | 1065 | 87.5 | 152 | 12.5 |
Yes | 82 | 86.3 | 13 | 13.7 | 0 | 0 | 0 | 0 | 82 | 86.3 | 13 | 13.7 |
Stroke | ||||||||||||
No | 697 | 87.2 | 102 | 12.8 | 438 | 87.8 | 61 | 12.2 | 1135 | 87.4 | 163 | 12.6 |
Yes | 11 | 84.6 | 2 | 15.4 | 1 | 100.0 | 0 | 0 | 12 | 85.7 | 2 | 14.3 |
D Diopter
EGPS European Glaucoma Prevention Study
OHTS Ocular Hypertension Treatment Study
POAG Primary open angle glaucoma