Values represent 5 min segments for pre-IH (open bars) and post-IH (filled bars). A, burst frequency increased significantly over time and remained elevated after the hypoxic exposure, and was significantly higher post-IH. B, amplitude increased significantly over time and remained elevated after the 20 min hypoxic exposure; however, no significant difference between pre- and post-IH was observed. C, total MSNA increased significantly over time and remained elevated after the hypoxic exposure. There was a trend for total MSNA to be higher post-IH (P = 0.06). *Significantly different from baseline (P < 0.05). †Significantly different from pre-IH (P < 0.05).