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. 2006 Jun 29;575(Pt 3):961–970. doi: 10.1113/jphysiol.2006.114660

Table 1.

Cardiovascular and ventilatory measures pre and post exposure to intermittent hypoxia (IH)

Hypoxia Recovery
Baseline eupnoea 5 min 10 min 15 min 20 min 25 min 30 min 35 min 40 min
Pre-IH
  SBP (mmHg) 111 ± 3 118 ± 3* 117 ± 3* 120 ± 3* 120 ± 3* 112 ± 3 114 ± 3 114 ± 3 113 ± 3
  DBP (mmHg) 67 ± 3 67 ± 3 66 ± 4 66 ± 2 65 ± 3 69 ± 2 67 ± 3 69 ± 4 67 ± 3
  MAP (mmHg) 89 ± 2 98 ± 4* 97 ± 4* 101 ± 4* 99 ± 4* 90 ± 3 91 ± 2 91 ± 2 91 ± 2
  HR (beats min−1) 57 ± 3 68 ± 4* 68 ± 4* 67 ± 4* 67 ± 4* 56 ± 3 57 ± 3 57 ± 3 60 ± 3
graphic file with name tjp0575-0961-mu5.jpg 7.3 ± 1.0 10.9 ± 1.4* 10.6 ± 1.5* 10.3 ± 1.4* 9.8 ± 1.4* 7.4 ± 1.1 7.4 ± 1.1 7.5 ± 1.2 7.5 ± 1.2
  fb (breaths min−1) 12.6 ± 1.2 14.6 ± 1.1* 14.9 ± 1.1* 14.7 ± 0.9* 15.2 ± 1.0* 14.6 ± 1.1* 14.8 ± 1.18 14.4 ± 1.1* 13.5 ± 1.2
  VT (l) 0.81 ± 0.12 1.10 ± 0.08* 0.99 ± 0.11* 0.92 ± 0.90* 0.92 ± 0.13* 0.79 ± 0.12* 0.75 ± 0.13* 0.74 ± 0.09 0.80 ± 0.15
  PET,CO2 (mmHg) 41.4 ± 0.8 42.0 ± 1.1 41.2 ± 1.2 41.1 ± 1.4 41.3 ± 1.2 41.5 ± 0.8 41.2 ± 1.0 41.3 ± 1.1 41.6 ± 1.3
  SaO2 (%) 97.3 ± 0.3 80.9 ± 1.0* 80.8 ± 1.0* 80.5 ± 0.8* 80.4 ± 1.0* 94.4 ± 0.4 97.4 ± 0.2 97.4 ± 0.2 97.4 ± 0.2
Post-IH
  SBP (mmHg) 113 ± 4 119 ± 4* 121 ± 4* 117 ± 3* 120 ± 4* 116 ± 3 114 ± 4 115 ± 3 116 ± 3
  DBP (mmHg) 71 ± 2 71 ± 3 70 ± 3 70 ± 3 69 ± 2 68 ± 3 69 ± 2 69 ± 2 70 ± 3
  MAP (mmHg) 90 ± 3 96 ± 3* 98 ± 3* 94 ± 2* 97 ± 4* 94 ± 3* 92 ± 3 92 ± 3 92 ± 2
  HR (beats min−1) 59 ± 4 69 ± 5* 67 ± 4* 68 ± 4* 67 ± 4* 57 ± 3 58 ± 4 58 ± 3 58 ± 3
graphic file with name tjp0575-0961-mu6.jpg 6.4 ± 1.2 9.8 ± 1.7* 9.7 ± 1.8* 9.3 ± 1.7* 8.9 ± 1.6* 6.3 ± 1.1 6.4 ± 1.2 6.5 ± 1.2 6.6 ± 1.2
  fb (breaths min−1) 12.9 ± 1.0 14.2 ± 1.1* 14.0 ± 1.2* 13.8 ± 1.1 13.2 ± 1.1 12.7 ± 1.0 12.7 ± 1.1 12.6 ± 0.9 12.2 ± 0.9
  VT (l) 0.75 ± 0.07 1.00 ± 0.06* 1.00 ± 0.07* 1.00 ± 0.07* 0.96 ± 0.07* 0.71 ± 0.04 0.72 ± 0.03 0.75 ± 0.03 0.75 ± 0.05
  PET,CO2 (mmHg) 41.2 ± 0.9 41.7 ± 1.2 41.6 ± 1.4 41.2 ± 1.5 41.3 ± 1.7 41.7 ± 1.2 40.9 ± 1.2 41.0 ± 1.3 41.4 ± 1.2
  SaO2 (%) 97.4 ± 0.1 79.7 ± 0.5 80.5 ± 0.5 80.2 ± 0.7 79.9 ± 0.3 94.6 ± 0.3 97.6 ± 0.4 97.7 ± 0.3 97.7 ± 0.1

SBP = systolic blood pressure; DBP = diastolic blood pressure; MAP = mean arterial pressure; HR = heart rate; Inline graphic; fb = breathing frequency; VT = tidal volume; PET,CO2 = end-tidal partial pressure of carbon dioxide; SaO2 = oxyhaemoglobin saturation.

*

Significantly different from baseline (P < 0.05).