Figure 10.

Peripheral localization of DIM-7 is Corkscrew dependent. (A) Integrin-expressing cells were spread on RBB-Tiggrin and stained for DIM-7. Note the DIM-7 staining around virtually the entire periphery in this cell (arrows). (B) DIM-7 peripheral localization is absent in cells that have been treated with dsRNA against corkscrew, although DIM-7 staining seems greater overall than in A; Western blots confirm that DIM-7 levels increase in cells with reduced Corkscrew (data not shown). Bar, 10 μm.