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. 1998 Mar 31;95(7):4061–4065. doi: 10.1073/pnas.95.7.4061

Figure 1.

Figure 1

Genomic organization of the mouse UCP3 and UCP2 genes. The mouse UCP3 gene is 5′ relative to the UCP2 gene. The distance between the two genes is close to 8 kb. This organization and the calculation of the distance between the two genes was predicted from PCR experiments on genomic DNA from two different strains of mice (see Materials and Methods). Roman numerals correspond to exons. The +1 position refers to the transcriptional start site of the mouse UCP2 gene determined from primer extension experiments (S.R., C. Pecqueur, and D.R., unpublished data). For UCP2 genomic structure, a genomic clone referred to as clone mmU2L2 was isolated from a mouse 129/SvJ genomic library in the λ FIXIT vector (Stratagene library 946306) and entirely sequenced. The mmU2L2 clone contains 7.1 kb of DNA upstream from the transcriptional start site (S.R. and D.R., unpublished data).