Figure 5.
Conformational Flexibility of α-Helical Hairpin
(A) Comparison of four conformations of AcrA(45-312)-4M observed in the crystal, with molecules A, B, C, and D superposed on the lipoyl domain and displayed as Cα traces. The greatest difference, ∼15°, is between molecules B and C.
(B) Comparison of the 13 conformations of MexA observed in its crystal, with molecules superposed on the lipoyl domain and displayed as Cα traces.
(C) Superposition of molecule B of AcrA(45-312)-4M (orange) and molecule M of MexA (purple), with molecules superposed on all domains and displayed as Cα traces.