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Response of ICa-L to isoproterenol and carbachol in ventricular myocytes from wild-type and Gαo−/− mice
| Condition | % ICa-L activity (n)
|
|
|---|---|---|
| Gαo+/+ | Gαo−/− | |
| No agonist | 100 | 100 |
| Isoproterenol | 241 ± 27 (9) | 244 ± 29 (10) |
| Isoproterenol plus carbachol | 106 ± 14 (9) | 212 ± 37 (10) |
The data are tabulated from experiments performed as described in Fig. 5 and given as mean ± SD for the number of cells tested (n). The cells came from four Gαo+/+ and five Gαo−/− mice.
