AQP0 |
AQP |
Water |
Lens of the eye |
AQP1 |
AQP |
Water |
Kidney (proximal tubule and thin descending limb of the loop of Henle), erythrocytes, capillary endothelium, choroid plexus, corneal epithelium, ear, lung, GI tract, skeletal muscle, heart muscle |
AQP2 |
AQP |
Water |
Kidney (principal cells of the collecting duct and connecting tubules; apical surface and subapical vesicles) |
AQP3 |
GLP |
Urea and glycerol; water |
Kidney (principal cells of the collecting duct and connecting tubules; basolateral surface), airways, lung, GI tract, brain, ear, urinary bladder, cornea, epidermis |
AQP4 |
AQP |
Water |
Kidney (collecting duct principal cells; basolateral), retina, ear, airways, lung, GI tract, fast-twitch skeletal muscle, glial cells at blood brain barrier, astrocytes |
AQP5 |
AQP |
Water |
Salivary gland, lacrimal gland, trachea, epithelia of nasopharynx and airways, alveolar type 1 cells, ear, eye, placenta, pancreas |
AQP6 |
AQP |
Anions (NO−3 and Cl−; water |
Kidney (intracellular vesicles in type A intercalated cells of the collecting duct) |
AQP7 |
GLP |
Urea and glycerol; water, arsenite |
Testis, sperm, kidney (proximal tubule), adipose tissue, skeletal muscle |
AQP8 |
AQP |
Urea and NH3, water |
Testis, sperm, GI tract, placenta, kidney (proximal tubule and collecting duct), airways, liver, salivary glands, glial and neuronal cells, pancreas |
AQP9 |
GLP |
Urea and glycerol; water, arsenite |
Liver, testis, sperm, spleen, brain, leukocytes, kidney, lung, brain (astrocytes and ependymal cells) |
AQP10 |
GLP |
Urea and glycerol; water |
Duodenum, jejunum |
AQP11 |
*SuperAQP |
Unknown |
Kidney (intracellular localization in proximal tubule), liver, testis, brain |
AQP12 |
*SuperAQP |
Unknown |
Pancreas (acinar cells) |