Table 1 .
Characteristics of normal control volunteers and diabetic patients recruited for this study
| Participant type | n | Sex M/F | Age (years) | Duration of diabetes (years) | BMI (kg/m2) | GFR (ml/min) | Fasting plasma glucose (mmol/l) | HbA1c (%) | Systolic BP (mmHg) | Diastolic BP (mmHg) | ACE inhibitor/ARB therapy |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Control volunteers | 20 | 10/10 | 53 ± 10 | – | 27 ± 4 | 89 ± 18 | 5.6 ± 0.8 | 5.0 ± 0.2 | ND | ND | – |
| Type 1 diabetes | 26 | 10/16 | 48 ± 15 | 22.1 ± 13.3 | 28 ± 5 | 93 ± 28 | 9.2 ± 1.7* | 8.7 ± 1.2* | 131 ± 21 | 73 ± 11 | 9 |
| Type 2 diabetes | 48 | 29/19 | 62 ± 12 | 13.0 ± 8.9** | 31 ± 6 | 92 ± 30 | 9.1 ± 2.2* | 8.6 ± 1.8* | 141 ± 22 | 77 ± 9 | 33 |
Data are mean±SD.
ND Not determined
*p < 0.001 with regard to normal volunteers
**p < 0.01 with regard to type 1 diabetes (Mann–Whitney U test)