Table 1 Percentage of cases showing vascular endothelial growth factor and tissue factor expression across the adenoma–carcinoma sequence.

Phase of ACS	Sample size	Percentage expression of VEGF (%)	Percentage expression of TF (%)
Low grade dysplasia polyps	47	57	63
High grade dysplasia polyps	19	80	80
Intra‐polyp carcinoma	30	90	67
Dukes' A carcinoma	10	70	40
Dukes' B carcinoma	26	58	52
Dukes' C carcinoma	26	65	37

ACS, Adenoma–carcinoma sequence; TF, tissue factor; VEGF, vascular endothelial growth factor. VEGF expression was identified in 74% of the carcinoma specimens (including intra‐polyp carcinoma; IPC). In total, 51% of the carcinomas (including IPC) included in the study expressed TF.