Table 3 Univariate analysis of pathological prognostic factors.
| Factor | Category | Petersen (colon) | Yorkshire (colon) | Yorkshire (rectal) | Yorkshire (colorectal) | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Survival (95% CI) | χ2 | p Value | Survival (95% CI) | χ2 | p Value | Survival (95% CI) | χ2 | p Value | Survival (95% CI) | χ2 | p Value | ||
| Extent of spread beyond muscularis propria | <3 mm | 89.3 (78.7 to 94.7) | 15.0 (2) | 0.0006 | 74.0 (69.1 to 78.2) | 33.3 (4) | <0.0001 | 76.2 (70.2 to 81.2) | 26.4 (4) | <0.0001 | 74.8 (71.1 to 78.2) | 54.7 (4) | <0.0001 |
| 3–5 mm | 76.9 (67.2 to 84.1) | 70.3 (60.7 to 78.8) | 68.2 (55.0 to 78.3) | 69.6 (62.1 to 76.0) | |||||||||
| >5 mm | 61.5 (48.7 to 72.0) | 65.8 (58.7 to 72.0) | 53.9 (42.8 to 63.7) | 62.1 (56.2 to 67.8) | |||||||||
| Not reported T3 | – | 67.9 (60.1 to 74.4) | 72.4 (60.2 to 81.5) | 69.2 (62.8 to 74.7) | |||||||||
| Not reported T4 | – | 54.7 (47.6 to 61.2) | 44.8 (31.7 to 57.0) | 52.5 (46.2 to 58.3) | |||||||||
| Peritoneal involvement | Absent | 87.1 (80.2 to 91.7) | 21.7 (1) | <0.0001 | 70.1 (66.6 to 73.2) | 24.8 (2) | <0.0001 | 71.0 (66.3 to 75.2) | 23.5 (2) | <0.0001 | 70.4 (67.6 to 72.9) | 41.0 (2) | <0.0001 |
| Present | 59.9 (49.4 to 68.6) | 54.9 (47.4 to 61.7) | 39.1 (24.4 to 53.5) | 52.0 (45.3 to 58.3) | |||||||||
| Not reported | – | 70.5 (60.5 to 78.4) | 62.7 (50.2 to 72.9) | 67.2 (59.5 to 73.2) | |||||||||
| Venous invasion | Not evident | 83.7 (76.2 to 89.0) | 15.2 (1) | 0.0001 | 69.7 (66.5 to 72.7) | 12.7 (2) | 0.0017 | 69.9 (65.2 to 74.1) | 15.6 (2) | 0.0004 | 69.8 (67.1 to 72.2) | 25.0 (2) | <0.0001 |
| Present | 73 (49.4 to 87.0) | 56.3 (46.3 to 65.1) | 52.2 (40.1 to 63.1) | 54.6 (47.0 to 61.6) | |||||||||
| Not reported | – | 59.1 (48.3 to 68.4) | 68.1 (50.7 to 80.5) | 61.7 (52.8 to 69.5) | |||||||||
| Margin involvement | Not involved | 78.7 (72.3 to 83.7) | 7.3 (1) | 0.007 | 68.9 (65.9 to 71.8) | 29.5 (2) | <0.0001 | 71.3 (66.7 to 75.4) | 14.2 (2) | 0.0008 | 69.6 (67.1 to 72.0) | 39.1 (2) | <0.0001 |
| Present | 55.3 (35.8 to 73.6) | 41.5 (28.3 to 54.1) | 48.0 (36.6 to 58.5) | 45.2 (36.6 to 53.5) | |||||||||
| Not reported | – | 66.6 (49.4 to 79.2) | 59.8 (33.6 to 78.5) | 64.5 (50.4 to 75.5) | |||||||||
| Tumour perforation | Absent | 76.6 (70.5 to 81.7) | 9.3 (1) | 0.0023 | 73.8 (67.7 to 79.0) | 21.0 (2) | <0.0001 | 77.0 (68.6 to 83.4) | 6.6 (2) | 0.04 | 75.0 (70.1 to 79.1) | 26.0 (2) | <0.0001 |
| Present | 46.8 (14.8 to 73.9) | 46.4 (30.9 to 60.4) | 52.8 (28.9 to 72.0) | 48.2 (35.3 to 60.0) | |||||||||
| Not reported | – | 66.6 (63.1 to 69.9) | 64.8 (59.7 to 69.4) | 66.0 (63.1 to 68.7) | |||||||||
| Dukes C, one positive node | – | 58.4 (52.2 to 64.1) | 57.4 (50.1 to 63.9) | 57.9 (53.3 to 62.3) | |||||||||