Table 2 Use of azathioprine in the 37 patients who developed nodular regenerative hyperplasia.
Variable | |
---|---|
Indication for azathioprine (n (%)) | |
Chronic active, steroid dependent or steroid refractory | 28 (76) |
disease | |
Postoperative prophylaxis/recurrence | 2 (5) |
Extensive Crohn's disease of the small intestine | 7 (19) |
Azathioprine dose (median (range)) | |
At data entry (mg/kg/d) | 2 (1.5 to 3.0) |
Duration of azathioprine treatment (months) (median (range)) | |
All patients | 37 (3 to 165) |
Patients with portal hypertension (n = 31) | 34 (3 to 159) |
Patients without portal hypertension (n = 6) | 37.5 (16 to 165) |
Time between start of azathioprine and discovery of NRH (months) (median (range)) | 48 (6 to 187) |
NRH, nodular regenerative hyperplasia.