. Author manuscript; available in PMC: 2008 Aug 16.

Published in final edited form as: J Control Release. 2007 Apr 19;121(1-2):19–27. doi: 10.1016/j.jconrel.2007.04.007

Table 1.

Properties of Nanogels with regular (NG) and biodegradable network (NGss)

Nanogel	Nitrogen content, μmol/mg^*	Nanogel diameter, nm	Diameter of NTP-loaded Nanogel, nm	Cytotoxicity, (CC₅₀, μg/ml^)†

NG(PEG)	6.5	152 ± 6	84 ± 3	70
NG(PEGss)	6.1	100 ± 8	58 ± 2	250
NG(F127)	5.8	132 ± 4	69 ± 1	80
NG(F127ss)	5.5	187 ± 6	112 ± 3	190
NG(F68)	6.2	176 ± 4	74 ± 0.5	95
NG(F68ss)	6.4	120 ± 5	67 ± 2	250
PEI 25kDa	23	n/a	n/a	5
PEIss	21.4	n/a	n/a	36

All Nanogels have nearly the same PEI content, 25 ± 4% (wt), determined by elemental analysis.

^†

Based on MTT assay after 24h-incubation of ATP-loaded Nanogels with human breast carcinoma MCF-7 cells.