Structural domains of the Y-family polymerases. The polymerase domain is labeled in red (palm), blue (finger), green (thumb), purple (LF), and yellow (N-terminal addition in polκ and Rev1). The regulatory units are color- and shape-coded as indicated at the bottom of the figure. UBM stands for ubiquitin-binding motif, UBZ for ubiquitin-binding zinc finger, and BRCT for Brca1 C-terminal domain.