Fig. 6.

Pictorial representation of the shortest paths (between Leu-13 and the anticodon binding residues Trp-461, Asn-391, and Arg-395) shown in Fig. 5 [(a) paths I and III; (b) paths II and IV)]. In both a and b, the residues participating in the communication paths and MetAMP are shown as spheres, MetAMP is shown in magenta, and Leu-13 and Trp-461 are shown in orange. The residues common between the paths I and III in a and between II and IV in b also are shown in orange. The residues that are exclusive to paths I and III are shown in violet and blue, respectively, in a, and the residues that are exclusive to paths II and IV are shown in yellow and cyan, respectively, in b. Light green, anticodon binding domain; gray, active site and KMSKS domains; purple blue, linker peptide; lemon green, CP domain; brown, tRNA.