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IKKα kinase activation is required for full mammary tumorigenesis by MMTV-c-neu. Occurrence of mammary cancer in Ikkα +/+/MMTV-c-neu, Ikkα AA/AA/MMTV-c-neu, Ikkα+/+/MMTV-v-Ha-ras, Ikkα AA/AA/MMTV-v-Ha-ras, Ikkα+/+/MMTV-c-myc, Ikkα AA/AA/MMTV-c-myc, Ikkα+/+/MMTV-Wnt1, and Ikkα AA/AA/MMTV-Wnt1 mice that were followed for 1 year and in Ikkα+/+/MMTV-PyMT and Ikkα AA/AA/MMTV-PyMT mice that were followed for 4 months. WT, Ikkα+/+; AA, Ikkα AA/AA.
