Fig. 1.

PCR validation of microarray findings. PCR validation of selected genes differentially expressed in epithelial brushings from asthmatic subjects compared with healthy control subjects (A) and genes responsive to corticosteroids in the clinical trial of inhaled fluticasone in asthmatics (B).^§§ Fold induction by microarray was statistically significant (P < 0.05, Bonferroni corrected) for all genes shown. Fold induction by PCR (for validation) was statistically significant (P < 0.05) for all genes except the periostin response to fluticasone (POSTN, P = 0.064).