Table 2.

F9 antigen level and coagulant activity after gentamicin treatment (34 mg/kg s.c.) after 2 days of pretreatment

Mice	F9 antigen, ng/100 μl	F9 coagulant activity, %
R338X (n = 6)	2.82 ± 0.42*	3.38 ± 0.82†
R29X (n = 9)	1.85 ± 0.15	2.73 ± 0.56
HB (n = 4)	2.06 ± 0.16	2.6 ± 0.55

Untreated R338X mice, treated and untreated HB mice, and treated and untreated R29X mice have indistinguishable baseline F9 antigen and F9 coagulant activities. Time elapsed was 3, 9, and 48 h after last treatment. No differences were observed in antigen level or coagulant activity between these three time points.

*P = 0.0017, R338X antigen level compared with R29X antigen level.

^†R338X, R29X, and HB coagulant activities are not significantly different.