Table 2.
Factors which predict use of ≥ 5 drugs on admission to hospital among 827 patients
| Univariate | Multivariate | |||
|---|---|---|---|---|
| OR | 95% CI | OR | 95% CI | |
| Gender (female = 1) | 1.40 | (1.06, 1.85) | 1.54 | (1.14, 2.08) |
| Age per year | 1.03 | (1.02, 1.04) | 1.02 | (1.01, 1.03) |
| Diabetes mellitus | 2.46 | (1.56, 3.87) | 2.18 | (1.34, 3.52) |
| Cardiac failure | 2.70 | (1.86, 3.93) | 1.68 | (1.12, 2.51) |
| Reduced renal function | 2.58 | (1.79, 3.71) | 1.72 | (1.16, 2.55) |
| Reduced liver function | 0.88 | (0.32, 2.39) | – | – |
| History of allergy or adverse reactions to drugs | 1.10 | (0.75, 1.60) | – | – |
| Non-adherence | 1.04 | (0.50, 2.19) | – | – |
| Use of drugs with narrow therapeutic index | 2.31 | (1.70, 3.14) | 1.77 | (1.28, 2.46) |
| Others | 1.11 | (0.76, 1.63) | – | – |
OR, Odds ratio; CI, confidence interval. Variables analysed by a logistic regression with≥5 drugs on admission as the dependent variable, and gender, age and the clinical/pharmacological risk factors as independent variables.