Table 3.

Signs and symptoms of adverse drug reactions

Signs and symptoms	n = 460 (%)
Cardiovascular (postural arterial hypotension, heart rhythm or conduction disorders)	145 (31.5)
Ionic or renal effect (dehydration, ionic disorders, renal failure)	112 (24.3)
Neuropsychological (vigilance impairment, agitation, confusion, extrapyramidal syndrome, sleep disorder)	63 (13.7)
Digestive (diarrhoea, vomiting, constipation, hepatic or pancreas disorders*)	40 (8.7)
Digitalis toxicity	33 (7.2)
Metabolic (dysglycaemia, dysthyroidism, gynecomastia, SIADH, adrenal failure, phosphorus-calcium disorder)	30 (6.5)
Haematological (cytopenia, coagulation disorder, haemorrhage)	25 (5.4)
Cutaneous (rash, pruritus, urticaria)	4 (0.9)
Other	8 (1.8)

^*Eight hepatitis and two pancreatitis. SIADH, Syndrome of inappropriate antidiuretic hormone.