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. 2007 Jan 3;63(6):672–679. doi: 10.1111/j.1365-2125.2006.02832.x

Table 1.

Participants' characteristics at baseline and study end

Baseline Placebo Baseline Study end P vs. baseline ATV Baseline Study end P vs. baseline P placebo vs. ATV at baseline
N 12 12 12 12
Men, n (%) 6 (50) 6 (50) 6 (50) 6 (50)
Age (SD) 58.3 (5.0) 58.3 (5.0) 58.9 (7.3) 58.9 (7.3) 0.821
Body mass index, kg m−2 (SD) 25.3 (1.8) 25.3 (1.8) 24.2 (4.1) 24.2 (4.1) 0.405
Total cholesterol, mg dl−1 (SD) 284 (30) 289 (35) 0.844 320 (61) 182 (32) < 0.001 0.078
Low-density lipoprotein, mg dl−1 (SD) 202 (21) 206 (34) 0.469 231 (54) 103 (31) < 0.001 0.102
High-density lipoprotein, mg dl−1 (SD) 50.6 (13.1) 51.4 (11.5) 0.625 59.1 (11.6) 62.3 (11.8) 0.101 0.103
15-F2t-isoP urinary excretion, ng h−1 (IQR) 8.0 (6.4–11.1) 8.9 (7.4–12.3) 0.721 9.8 (6.6–12.5) 8.4 (6.9–13.3) 0.875 0.763
PLA2s activity, nmol min−1 ml−1 (SD) 4.35 (0.61) 5.25 (2.06) 0.172 4.12 (1.14) 4.45 (0.83) 0.247 0.599
PAF-AH activity, nmol min−1 ml−1 (SD) 16.7 (2.0) 17.3 (1.5) 0.196 16.1 (2.8) 10.9 (2.6) < 0.001 0.552
hsCRP, mg l−1 (IQR) 1.50 (0.70–2.37) 1.60 (0.70–2.00) 0.507 1.35 (0.83–1.80) 0.85 (0.70–2.17) 0.553 0.932

PLA2s, Phospholipases A2; PAF-AH, platelet-activating factor acetylhydrolase; hsCRP, ultra-sensitive C-reactive protein.