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Change of α1-adrenoceptor occupancy following 25 mg p.o. administration of milnacipran, fluvoxamine and imipramine
| Drug | A | B | Φ*/Φ° ( = A/B) |
|---|---|---|---|
| Milnacipran | 7.13 | >1.00, 1.02 | >7.00, 7.13 |
| Fluvoxamine | 1.01 | 1.01 | 1.00 |
| Imipramine | 4.63 | 1.08 | 4.12 |
; 
; Φ*/Φ° = A/B.
