Table 4.
Rate ratio (RR) of nonfatal coronary artery disease event for cases occurring after 1 year of follow-up and their controls
RR (95% CI) | |||
---|---|---|---|
Drug at initiation | Adherence 70% | Adherence 80% | Adherence 90% |
Atorvastatin | Reference | Reference | Reference |
Fluvastatin | 1.14 (0.82, 1.57) | 1.14 (0.82, 1.57) | 1.13 (0.82, 1.57) |
Lovastatin | 0.81 (0.46, 1.44) | 0.81 (0.46, 1.44) | 0.81 (0.46, 1.43) |
Pravastatin | 1.03 (0.84, 1.27) | 1.03 (0.83, 1.26) | 1.03 (0.84, 1.26) |
Simvastatin | 0.94 (0.74, 1.18) | 0.94 (0.74, 1.18) | 0.93 (0.74, 1.18) |
Statin adherence* | |||
< 70%, 80%, 90%, respectively, | Reference | Reference | Reference |
≥70%, 80%, 90%, respectively, | 0.86 (0.72, 1.02) | 0.86 (0.72, 1.03) | 0.81 (0.67, 0.97) |
Age (continuous)† | 1.02 (0.99, 1.04) | 1.02 (0.99, 1.04) | 1.02 (0.99, 1.04) |
Sex (male vs. female) | 1.38 (1.16, 1.63) | 1.38 (1.16, 1.63) | 1.37 (1.16, 1.63) |
Social assistance (yes vs. no)† | 1.30 (1.09, 1.55) | 1.30 (1.09, 1.55) | 1.31 (1.10, 1.57) |
Newly diagnosed diabetes mellitus (yes vs. no)‡ | 1.97 (1.20, 3.24) | 1.97 (1.20, 3.23) | 1.97 (1.20, 3.24) |
Antidiabetic drug adherence < 80%§ (yes vs. no) | 1.21 (0.92, 1.60) | 1.21 (0.92, 1.60) | 1.21 (0.92, 1.59) |
Antidiabetic drug adherence ≥80%§ (yes vs. no) | 0.86 (0.63, 1.17) | 0.86 (0.63, 1.17) | 0.87 (0.64, 1.18) |
Newly diagnosed hypertension (yes vs. no)‡ | 3.50 (2.59, 4.72) | 3.50 (2.60, 4.74) | 3.54 (2.62, 4.77) |
Antihypertensive drug adherence < 80%§ (yes vs. no) | 1.77 (1.42, 2.22) | 1.78 (1.42, 2.22) | 1.77 (1.42, 2.21) |
Antihypertensive drug adherence ≥80%§ (yes vs. no) | 1.72 (1.38, 2.13) | 1.72 (1.38, 2.13) | 1.74 (1.40, 2.15) |
Proportion of days covered (%).
At treatment initiation.
ICD-9 or pharmacological treatment; new diabetes or new hypertension was detected in the year before index date.
Proportion of days covered (%) in the year before the index date.