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. 2007 Jan 3;63(6):698–708. doi: 10.1111/j.1365-2125.2006.02828.x

Table 4.

Rate ratio (RR) of nonfatal coronary artery disease event for cases occurring after 1 year of follow-up and their controls

RR (95% CI)
Drug at initiation Adherence 70% Adherence 80% Adherence 90%
Atorvastatin Reference Reference Reference
Fluvastatin 1.14 (0.82, 1.57) 1.14 (0.82, 1.57) 1.13 (0.82, 1.57)
Lovastatin 0.81 (0.46, 1.44) 0.81 (0.46, 1.44) 0.81 (0.46, 1.43)
Pravastatin 1.03 (0.84, 1.27) 1.03 (0.83, 1.26) 1.03 (0.84, 1.26)
Simvastatin 0.94 (0.74, 1.18) 0.94 (0.74, 1.18) 0.93 (0.74, 1.18)
Statin adherence*
  < 70%, 80%, 90%, respectively, Reference Reference Reference
 ≥70%, 80%, 90%, respectively, 0.86 (0.72, 1.02) 0.86 (0.72, 1.03) 0.81 (0.67, 0.97)
Age (continuous) 1.02 (0.99, 1.04) 1.02 (0.99, 1.04) 1.02 (0.99, 1.04)
Sex (male vs. female) 1.38 (1.16, 1.63) 1.38 (1.16, 1.63) 1.37 (1.16, 1.63)
Social assistance (yes vs. no) 1.30 (1.09, 1.55) 1.30 (1.09, 1.55) 1.31 (1.10, 1.57)
Newly diagnosed diabetes mellitus (yes vs. no) 1.97 (1.20, 3.24) 1.97 (1.20, 3.23) 1.97 (1.20, 3.24)
Antidiabetic drug adherence < 80%§ (yes vs. no) 1.21 (0.92, 1.60) 1.21 (0.92, 1.60) 1.21 (0.92, 1.59)
Antidiabetic drug adherence ≥80%§ (yes vs. no) 0.86 (0.63, 1.17) 0.86 (0.63, 1.17) 0.87 (0.64, 1.18)
Newly diagnosed hypertension (yes vs. no) 3.50 (2.59, 4.72) 3.50 (2.60, 4.74) 3.54 (2.62, 4.77)
Antihypertensive drug adherence < 80%§ (yes vs. no) 1.77 (1.42, 2.22) 1.78 (1.42, 2.22) 1.77 (1.42, 2.21)
Antihypertensive drug adherence ≥80%§ (yes vs. no) 1.72 (1.38, 2.13) 1.72 (1.38, 2.13) 1.74 (1.40, 2.15)
*

Proportion of days covered (%).

At treatment initiation.

ICD-9 or pharmacological treatment; new diabetes or new hypertension was detected in the year before index date.

§

Proportion of days covered (%) in the year before the index date.