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. 2006 Nov 10;63(6):648–664. doi: 10.1111/j.1365-2125.2006.02820.x

Figure 7.

Figure 7

Dynamics of the hypothalamic–pituitary–gonadal axis compartments. Population-predicted drug, feedback, luteinizing hormone (LH) pool, LH and testosterone profiles after single subcutaneous administration of 3.75 mg of the gonadotropin-releasing hormone (GnRH) agonist triptorelin (dashed line) and 200 mg of the GnRH receptor blocker degarelix (solid line). The dotted line represents the castration concentration of 0.5 ng ml−1