Table 2.
Distribution of plasma concentrations of NNRTI and PI
| Antiretroviral drug | Number | Concentration (mg l−1)† | CV (%) | Optimal n (%) |
|---|---|---|---|---|
| Nevirapine | 18 | 5.31 (2.13) | 40.1 | 5 (27.8) |
| Efavirenz | 42 | 3.62 (1.70) | 46.9 | 26 (61.9) |
| Lopinavir | 43 | 7.26 (3.91) | 53.8 | 35 (81.4) |
| Nelfinavir | 7 | 3.02 (1.11) | 36.7 | 7 (100) |
| Saquinavir/ritonavir | 1 | 0.350 | 1 (100) | |
| Amprenavir/ritonavir | 2 | 2.06 (1.66–2.45)‡ | 2 (100) | |
| Atazanavir | 3 | 0.67 (0.62–1.52)‡ | 3 (100) | |
| Indinavir | 1 | 0.10 | 1 (100) | |
| Total | 117 | 80 (68.4) |
CV: coefficient of variation
†
data are expressed as mean (SD), except where noted.
‡
median (interquartile range).