Table 5.
Exacerbation of reflux symptoms in association with calcium antagonst (CA) therapy
| Heartburn | Acid reflux | Chest pain | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Frequency | Severity | Frequency | Severity | Frequency | Severity | |||||||
| CA | n | % | n | % | n | % | n | % | n | % | n | % |
| Nifedipine | 6 | 31.6 | 6 | 31.6 | 6 | 27.3 | 9 | 40.9 | 4 | 80.0 | 3 | 60.0 |
| Amlodipine | 8 | 40.0 | 5 | 25.0 | 10 | 43.5 | 8 | 34.8 | 3 | 75.0 | 3 | 75.0 |
| Felodipine | 7 | 33.3 | 3 | 14.3 | 6 | 42.9 | 4 | 28.6 | 0 | 0.0 | 0 | 0.0 |
| Verapamil | 5 | 29.4 | 3 | 17.6 | 4 | 22.2 | 3 | 16.7 | 1 | 33.3 | 1 | 33.3 |
| Diltiazem | 0 | 0.0 | 0 | 0.0 | 1 | 7.7 | 0 | 0.0 | 1 | 25.0 | 1 | 25.0 |
| Total | 26 | 44.1 | 17 | 28.8 | 27 | 45.8 | 24 | 40.7 | 9 | 15.2 | 8 | 13.6 |