Table 1.
Clinical characteristics and origin of neuropathic pain in the different cohorts [n; mean ± SD; (range); safety analysis set]
| Cohort 1 125 µg | Cohort 2 250 µg | Cohort 3 500 µg | Cohort 4 750 µg | |
|---|---|---|---|---|
| n | 12 | 12 | 14 | 2 |
| History of hypertension | 3 | 4 | 8 | 0 |
| Age (years) | 54.8 ± 9.7 | 53.0 ± 14.5 | 56.4 ± 10.2 | 62.5 ± 16.3 |
| (range) | (40–74) | (32–73) | (40–72) | (51–74) |
| Sex (male/female) | 8/4 | 5/7 | 8/6 | 2/0 |
| Height (cm) | 173 ± 11 | 170 ± 9 | 171 ± 8 | 185 ± 0 |
| Weight (kg) | 83 ± 18 | 79 ± 19 | 81 ± 18 | 101 ± 8 |
| Postherpetic pain (n) | 3 | 2 | 0 | 1 |
| Diabetic neuropathy (n) | 0 | 3 | 8 | 0 |
| Post-traumatic injury (n) | 6 | 6 | 4 | 1 |
| CRPS I (n) | 2 | 0 | 1 | 0 |
| CRPS 2 (n) | 1 | 1 | 1 | 0 |
CRPS, chronic regional pain syndrome.