Table 3.

Visual analog scale for the 125–500-µg cohorts at baseline and during the observational period (mean ± SD)

	Baseline		2 h		6 h		12 h		24 h
	CNS5161	Placebo	CNS5161	Placebo	CNS5161	Placebo	CNS5161	Placebo	CNS5161	Placebo
125 µg	64 ± 16	64 ± 17	50 ± 25	51 ± 22	50 ± 28	47 ± 27	51 ± 30	46 ± 29	53 ± 26	52 ± 30
250 µg	62 ± 13	55 ± 10	48 ± 20	43 ± 21	50 ± 18	41 ± 22	50 ± 19	44 ± 21	50 ± 20	50 ± 15
500 µg	65 ± 20	65 ± 18	54 ± 23	58 ± 20	53 ± 25	59 ± 23	55 ± 27	63 ± 23	56 ± 31	57 ± 24