Table 1.
General characteristics of the participants
| Subjects | Control | Impaired kidney function | anova (P value) |
|---|---|---|---|
| Gender (female/male) | 5/12 | 5/5 | – |
| Age (years) | |||
| Mean ± SD | 27.3 ± 9.3 | 39.6 ± 3.8 | 0.001 |
| Range | 21–50 | 32–43 | – |
| Weight (kg) | 73.9 ± 8.9 | 78.2 ± 18.6 | NS |
| Height (cm) | 177 ± 0.08 | 172 ± 0.08 | NS |
| BMI (kg m−2) | 23.5 ± 2.0 | 26.4 ± 5.3 | NS |
| eGFR* (ml min−1) | 119 ± 14.9 | 30.9 ± 10.8 | <0.0001 |
| fP-Creatinine (µmol l−1) | 86.1 ± 16.1 | 317 ± 99.2 | <0.0001 |
| P-ALT (U l−1) | 20.1 ± 8.1 | 20.2 ± 9.9 | NS |
| P-Alb (g l−1) | – | 38.4 ± 5.1 | – |
The results are presented as mean ± SD. BMI, body mass index; eGFR, estimated glomerular filtration rate; fP, fasting plasma; P, plasma; ALT, alanine aminotransferase; Alb, albumin. NS, not significant.
*
Calculated from the equation of Cockcroft-Gault.