Table 5.
Parameter | ≥6 months−≥1 yeara | <1 year−≤2 yearsb | ≥6 months−<1 yearc | ≥1 year−≤2 yearsd |
---|---|---|---|---|
AUC(0,∞) | ||||
Point estimate | 0.8204 | 0.9257 | 0.5187 | 0.8989 |
Lower 90% CI | 0.5552 | 0.6265 | 0.3791 | 0.6570 |
Upper 90% CI | 1.212 | 1.368 | 0.7096 | 1.230 |
Cmax | ||||
Point estimate | 0.6337 | 1.129 | 0.5394 | 1.117 |
Lower 90% CI | 0.5195 | 0.9256 | 0.4599 | 0.9523 |
Upper 90% CI | 0.7729 | 1.377 | 0.6327 | 1.310 |
≥6 months−<1 year (0.625 mg, n = 10) vs. adults (5 mg, n = 30)
≥6 months−<1 year (1.25 mg, n = 10) vs. adults (5 mg, n = 30)
≥1 year– ≤2 years (0.625 mg, n = 19) vs. adults (5 mg, n = 30
≥1 year – ≤2 years (1.25 mg, n = 19) vs. adults (5 mg, n = 30).