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Mean (% coefficient of variation) and median AUC(0,last) values for 3-OH-desloratadine in four poor metabolizers of desloratadine aged ≥6 months−<2 years
| Parameter | Both dose groups |
|---|---|
| Mean AUC(0,last) (ng ml−1 h) | 2.28 (123) |
| Median AUC(0,last) (ng ml−1 h) | 1.56 |
| Mean AUC(0,last) ratio (%) | 4.61 (111) |
| Median AUC(0,last) ratio (%) | 4.59 |
AUC(0,last) ratio = (AUC(3-OH-desloratadine) : AUC(desloratadine)) × 100.
