Table 2.
Linkage disequilibrium values (D' and r2), haplotype and genotype frequencies
| West African (n = 170) | African-American (n = 87) | ||
|---|---|---|---|
| SNP pair | |||
| 516-785 | D' | 1.000 | 0.923 |
| r2 | 0.719 | 0.853 | |
| 516-983 | D' | 0.688 | 0.997 |
| r2 | 0.025 | 0.047 | |
| 785-983 | D' | 0.995 | 0.997 |
| r2 | 0.037 | 0.047 | |
| Haplotype (allele) | |||
| 516G-785A-983T (*1) | 46.1% | 54% | |
| 516T-785G-983T (*6) | 41.5% | 34.8% | |
| 516T-785A-983T (*9) | 7.3% | 1.8% | |
| 516G-785A-983C (*18) | 4.2% | 7.5% | |
| 516G-785G-983T (*4) | n.o. | 1.8% | |
| 516T-785A-983C (?) | 0.8% | n.o. | |
| Genotype | |||
| *1/*18 | 2.9% | 10% | |
| *6/*18 | 4.1% | 4.6% | |
| *9/*18 | 1.8% | n.o. | |
| *6/516T-785A-983C | 0.6% | n.o. |
? new haplotype, warrants validation by cloning and sequencing; n.o. not observed.