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. 2006 Aug 10;577(Pt 1):369–386. doi: 10.1113/jphysiol.2006.115600

Figure 5. Kynurenic acid (Kyn) injection into rostral ventrolateral medulla (RVLM) greatly attenuate the peripheral chemoreflex in vagotomized rats.

Figure 5

A, response of the splanchnic and phrenic nerves to peripheral chemoreceptor stimulation with i.v. cyanide (NaCN: 50 μg kg−1) in a urethane-anaesthetized rat, before (left panel) and 5 min after bilateral injection of Kyn (200 mm, 50 nl: right panel) into RVLM. B, effect of Kyn on the cyanide-induced rise in MAP (*P < 0.05; 8 rats). C, effect of Kyn on the cyanide-induced rise in sSND (*P < 0.05; 8 rats).