Table 1.
Circulatory variables under each experimental condition
Heart rate (beats min−1) | MAP (mmHg) | |||||||
---|---|---|---|---|---|---|---|---|
Normoxia | Hyperoxia | Normoxia | Hyperoxia | |||||
FI,CO2 (%) | Cont | Indo | Cont | Indo | Cont | Indo | Cont | Indo |
0 | 62 ± 3 | 57 ± 2* | 60 ± 3 | 58 ± 4 | 74 ± 3 | 78 ± 3* | 75 ± 3 | 81 ± 3 |
2 | 60 ± 2 | 55 ± 3 | 58 ± 3 | 53 ± 3 | 75 ± 4 | 79 ± 2 | 75 ± 3 | 80 ± 2 |
4 | 61 ± 3 | 56 ± 3 | 60 ± 3 | 57 ± 3 | 75 ± 3 | 79 ± 2 | 75 ± 4 | 82 ± 2 |
6 | 71 ± 3 | 66 ± 4 | 67 ± 3 | 62 ± 3 | 79 ± 3 | 85 ± 2 | 79 ± 3 | 88 ± 2 |
CVR (mmHg cm−1 s−1) | PI | |||||||
---|---|---|---|---|---|---|---|---|
Normoxia | Hyperoxia | Normoxia | Hyperoxia | |||||
FI,CO2 (%) | Cont | Indo | Cont | Indo | Cont | Indo | Cont | Indo |
0 | 1.8 ± 0.2 | 2.4 ± 0.4 | 2.1 ± 0.2 | 2.7 ± 0.3 | 1.0 ± 0.2 | 1.2 ± 0.2 | 1.2 ± 0.3 | 1.2 ± 0.2 |
2 | 1.7 ± 0.2 | 2.3 ± 0.3 | 1.7 ± 0.1 | 2.8 ± 0.4 | 1.0 ± 0.1 | 1.1 ± 0.2 | 1.0 ± 0.1 | 1.2 ± 0.2 |
4 | 1.5 ± 0.1 | 2.3 ± 0.3 | 1.6 ± 0.1 | 2.7 ± 0.4 | 0.9 ± 0.1 | 1.1 ± 0.2 | 1.0 ± 0.1 | 1.2 ± 0.3 |
6 | 1.2 ± 0.1 | 2.2 ± 0.3 | 1.2 ± 0.1 | 2.3 ± 0.3 | 0.8 ± 0.1 | 1.0 ± 0.1 | 0.8 ± 0.1 | 1.0 ± 0.1 |
P < 0.05 compared to control. MAP, mean arterial pressure; CVR, cerebrovascular resistance; PI, pulsatility index; Cont, control group; Indo, indomethacin group.