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. 2006 Aug 24;577(Pt 1):141–154. doi: 10.1113/jphysiol.2006.118026

Figure 3. Pharmacological profile of the DHPG-induced reduction in peak current.

Figure 3

A, the DHPG-induced inhibition was blocked by mGluR1 antagonists (Ly367385, CPCCOEt and AIDA) but not by the mGluR5 antagonist MPEP. B, effect of the mGluR5 agonist CHPG on INaT evoked by a step from −70 to −20 mV. C, effect of DHPG on INaT in the presence of the PKC inhibitor BIS-I.