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. Author manuscript; available in PMC: 2008 Sep 7.
Published in final edited form as: Brain Res. 2007 Jul 27;1168:1–10. doi: 10.1016/j.brainres.2007.06.087

Figure 5. AICAR-induced stellation is associated with disassembled actin stress fibers and dispersed focal adhesions.

Figure 5

Cells were rinsed and maintained in HBSS for 2 h containing (A and D) growth media (GM), (B and E) vehicle (dH2O), or (C and F) 2mM AICAR. Cells immunostained for (A, B, C) Oregon Green labeled phalloidin toxin to visualize stress fibers or (D, E, F) monoclonal antibody against vinculin to visualize focal adhesions. Accompanying stellation, (C, arrows) stress fibers are disassembled and (F) focal adhesions are dispersed. Scale bar 25μm. Photomicrographs are representative of 3 independent experiments.