Table 1. Effect of simvastatin treatment on the intestinal radiation response in TM^+/+ and TM^Pro/− mice.

Influence of observation time (2 weeks vs. 26 weeks), genotype (TM^+/+ vs. TM^Pro/−), and simvastatin (simvastatin vs. no simvastatin) on radiation injury score, mucosal surface area, intestinal wall thickness, and subserosal thickness after localized intestinal irradiation mice.

Note that the p-values for the influence of genotype are not significant for any of the parameters, whereas, all p-values for the effect of simvastatin are highly significant.

	Term	F-ratio	p-value
Radiation injury score	Observation time	2.36	0.13
	Genotype	0.0	0.95
	Simvastatin	9.89	0.002
Mucosal surface area	Observation time	45.28	<0.0001
	Genotype	0.38	0.54
	Simvastatin	6.33	0.01
Intestinal wall thickness	Observation time	17.49	<0.0001
	Genotype	2.35	0.13
	Simvastatin	11.60	0.001
Subserosal thickness	Observation time	5.83	0.02
	Genotype	1.18	0.28
	Simvastatin	8.28	0.005