Table 1.

Dose–response for aspirin, paracetamol and ibuprofen from systematic reviews of comparisons with placebo in single-dose oral studies

Drug	Dose	Patients in comparison	NNT (95% CI)
Aspirin	600/650	5061	4.4 (4.0, 4.9)
	1000	716	4.0 (3.2, 5.4)
	1200	279	2.4 (1.9, 3.2)
Ibuprofen	200	1414	2.7 (2.4, 3.1)
	400	4703	2.4 (2.3, 2.6)
	800	76	1.6 (1.3, 2.2)
Paracetamol	500	561	3.5 (2.7, 4.8)
	600/650	1207	5.4 (4.2, 4.7)
	1000	2559	3.7 (3.3, 4.3)