Table 3.
Second-level analysis, using calculated numbers of patients with at least 50%maxTOTPAR
| Dose of drug (mg) | Number of | Percent with at least 50% pain relief | Higher vs. lower dose | |||||
|---|---|---|---|---|---|---|---|---|
| Drug | High | Low | Trials | Patients | High | Low | Relative benefit (95% CI) | NNT (95% CI) |
| Aspirin | 1000 | 500 | 2 | 301 | 62 | 52 | 1.2 (0.97, 1.4) | |
| Aspirin | 1200 | 600 | 6 | 608 | 39 | 34 | 1.2 (0.93, 1.4) | |
| Aspirin | 1000/1200 | 500/600 | 8 | 909 | 47 | 40 | 1.2 (1.01, 1.3) | 16 (8, >100) |
| Ibuprofen | 800 | 400 | 13 | 994 | 68 | 59 | 1.2 (1.1, 1.3) | 10 (6, 23) |
| Paracetamol | 1000 | 500/650 | 7 | 933 | 64 | 52 | 1.2 (1.1, 1.4) | 9 (6, 20) |