Table 1.
Summary of the number of high-quality urine and plasma samples per visit and treatment group available for 1H NMR spectrometry measurements
Run-in (V1) | Run-in (V2) | Post 2 week (V3) | Post 6 week (V5) | ||||||
---|---|---|---|---|---|---|---|---|---|
Treatment | Group | Urine | Plasma | Urine | Plasma | Urine | Plasma | Urine | Plasma |
Placebo | DF | 4 | 6 | 4 | 5 | 4 | 1 | 3 | 3 |
Placebo | HF | 4 | 4 | 4 | 4 | 4 | NA | 4 | 4 |
Placebo | DM | 4 | 5 | 4 | 5 | 4 | 2 | 2 | 2 |
Placebo | HM | 4 | 4 | 4 | 4 | 4 | NA | 4 | 4 |
RSG | DF | 4 | 2 | 4 | 4 | 4 | 1 | 3 | 3 |
RSG | HF | 4 | 4 | 4 | 3 | 4 | NA | 4 | 4 |
RSG | DM | 4 | 4 | 4 | 4 | 4 | 1 | 3 | 3 |
RSG | HM | 4 | 4 | 4 | 4 | 4 | NA | 4 | 4 |
Plasma samples collected on visit 3 (2-weeks post) were measured only if no sample was available at visit 5 (last observation carried forward). DF, Diabetic female; HF, healthy female; DM, diabetic male; HM, healthy male; RSG, rosiglitazone; Vx, visit x; NA, not analysed.