Table II.
Screening Inbred Mice by Tympanometry
| Strain | CR(ml) | VR(ml) | GR(ml) | PR(daPa) | CL(ml) | VL(ml) | GL(ml) | PL(daPa) |
|---|---|---|---|---|---|---|---|---|
| 129P1/ReJ | 0.41±0.05 | 0.22±0.01 | 0.07±0.02 | −117.14±19.45 | 0.35±0.07 | 0.21±0.01 | 0.04±0.02 | −109.71±18.32 |
| 129P3/J | 0.50±0.13 | 0.26±0.02 | 0.10±0.04 | −117.50±25.35 | 0.44±0.11 | 0.26±0.01 | 0.07±0.04 | −130.33±23.49 |
| 129S1/SvImJ | 0.52±0.14 | 0.29±0.07 | 0.12±0.05 | −83.06±21.39 | 0.50±0.16 | 0.26±0.06 | 0.11±0.06 | −77.92±29.54 |
| 129X1/SvJ | 0.65±0.18 | 0.25±0.04 | 0.16±0.07 | −62.46±24.71 | 0.52±0.15 | 0.27±0.06 | 0.13±0.05 | −67.67±20.63 |
| A/HeJ | 0.41±0.10 | 0.27±0.09 | 0.13±0.06 | −87.60±30.61 | 0.50±0.14 | 0.22±0.03 | 0.13±0.07 | −87.30±28.93 |
| BALB/cJ | 0.44±0.09 | 0.21±0.03 | 0.14±0.08 | −65.42±20.50 | 0.42±0.09 | 0.22±0.03 | 0.11±0.03 | −79.08±20.65 |
| BUB/BnJ | 0.45±0.11 | 0.26±0.06 | 0.10±0.04 | −95.48±43.09 | 0.46±0.09 | 0.26±0.04 | 0.12±0.08 | −101.52±50.47 |
| C57L/J | 0.65±0.11 | 0.22±0.02 | 0.15±0.05 | −103.50±13.61 | 0.68±0.09 | 0.23±0.02 | 0.16±0.04 | −97.08±15.65 |
| EL/SuzSeyFrkJ | 0.18±0.31 | 0.17±0.19 | 0.03±0.06 | −122.00±37.93 | 0.34±0.33 | 0.19±0.20 | 0.07±0.06 | −102.40±24.07 |
| FVB/NJ | 0.24±0.06 | 0.16±0.02 | 0.04±0.02 | −90.67±65.59 | 0.34±0.12 | 0.17±0.02 | 0.06±0.04 | −112.20±24.15 |
| I/LnJ | 0.42±0.12 | 0.24±0.01 | 0.05±0.03 | −130.25±21.38 | 0.47±0.11 | 0.25±0.01 | 0.07±0.03 | −138.83±28.89 |
| LP/J | 0.53±0.23 | 0.23±0.03 | 0.10±0.07 | −114.17±20.94 | 0.70±0.48 | 0.25±0.14 | 0.14±0.13 | −99.39±32.38 |
| NZB/BlNJ | 0.13±0.04 | 0.17±0.01 | 0.03±0.04 | −90.64±55.45 | 0.29±0.10 | 0.21±0.05 | 0.06±0.02 | −105.43±36.54 |
| PL/J | 0.54±0.13 | 0.23±0.03 | 0.09±0.04 | −132.85±27.99 | 0.53±0.14 | 0.23±0.02 | 0.09±0.04 | −130.42±33.81 |
| YBR/Ei | 0.44±0.12 | 0.25±0.04 | 0.07±0.03 | −133.08±23.58 | 0.52±0.08 | 0.26±0.04 | 0.09±0.03 | −87.50±32.97 |
| CBA/CaJ | 0.31±0.06 | 0.21±0.05 | 0.06±0.02 | −105.70±27.25 | 0.38±0.15 | 0.21±0.04 | 0.07±0.04 | −107.30±24.67 |
|
| ||||||||
| Grand Mean (n=61a) | 0.42±0.10 | 0.22±0.03 | 0.08±0.03 | −106.71±16.30 | 0.44±0.09 | 0.22±0.02 | 0.09±0.02 | −104.23±13.25 |
Tympanometry values were measured on each ear for at least 5 mice of each strain tested and the mean ± standard deviation calculated for each. In addition to the normal control strain CBA/CaJ, only the 15 strains that yielded abnormal tympanograms are listed in this table. Values that deviated from the grand mean by more than 2 standard deviation units were considered abnormal and are highlighted in bold and underlined. Tympanogram data for the other 45 strains whose parameters were all within the normal range are available as online supplemental material. Subscripts R and L indicate right and left ears, respectively. C,V,G and P are defined in Table I, Fig. 1, and in the text.
A grand mean was calculated for each value from all 61 strains of mice (5 mice per strain).