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. Author manuscript; available in PMC: 2008 Apr 1.
Published in final edited form as: Hum Pathol. 2007 Jan 19;38(4):585–592. doi: 10.1016/j.humpath.2006.09.014

Figure 5. Frequency of MSI-H and CIMP-high in colorectal cancer with various combined p53/p27 status.

Figure 5

The inverse association between cytoplasmic p27 and MSI-H (or CIMP-high) is much more pronounced in p53 negative tumors than in p53 positive tumors. For raw data, see Supplemental material 2. CIMP, CpG island methylator phenotype; MSI-H, microsatellite instability-high; p27C, p27 cytoplasmic; p27N, p27 nuclear.